These heartburn medications have a known history or affecting the heart and kidneys, but, according to a recent study published in The BMJ, taking PPIs can also cause stomach cancer. The study looked at over 157 000 participants who took prescription PPIs. After 10 years, they followed up on the participants and found that these subjects were, on average, 17% more likely to suffer a premature death than those who took H2 inhibitors.
More specifically, taking PPIs increased the patients’ risks of suffering from cardiovascular disease, kidney failure, and stomach cancer. Apart from being dangerous, PPIs are also overprescribed, with the study estimating that around half of their participants had no indication to take them and took them much longer than they had to.
This is very alarming, especially when you take into account that the duration of the treatment with PPIs proportionally increases one’s risks of death.
Since PPIs are prescribed so often and some of them are easily accessible over the counter, there should be more awareness about the dangers these medications pose to one's health. You should be especially careful about over-the-counter PPIs:
The findings of this study don’t mean that you shouldn’t seek treatment for acid reflux or heartburn altogether, as, apart from being painful, these conditions can develop into peptic ulcers that are very dangerous to your health. At the same time, it’s best if you avoid long-term PPI treatments and seek out a safer treatment with your doctor, especially if you have to take it long term.
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